Structure of PDB 6ahr Chain E

Receptor sequence
>6ahrE (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
VRFKHRYLLCELVSDDPRCRLSLDDRVLSSLVRDTIARVHGTFGAAACSI
GFAVRYLNAYTGIVLLRCRKEFYQLVWSALPFITYLENKGHRYPCFFNTL
HVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTRSCLL
3D structure
PDB6ahr Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
ChainE
Resolution3.92 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E R3 K5 R7 Y8 R56 T106 R108 R2 K4 R6 Y7 R55 T105 R107
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0033204 ribonuclease P RNA binding
Biological Process
GO:0001682 tRNA 5'-leader removal
GO:0006364 rRNA processing
GO:0008033 tRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005655 nucleolar ribonuclease P complex
GO:0005730 nucleolus
GO:0030677 ribonuclease P complex
GO:0030681 multimeric ribonuclease P complex
GO:1902555 endoribonuclease complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ahr, PDBe:6ahr, PDBj:6ahr
PDBsum6ahr
PubMed30454648
UniProtQ969H6|POP5_HUMAN Ribonuclease P/MRP protein subunit POP5 (Gene Name=POP5)

[Back to BioLiP]