Structure of PDB 5z3q Chain E

Receptor sequence
>5z3qE (length=201) Species: 12081 (Human poliovirus 1 Mahoney) [Search protein sequence]
SKHRIEPVCLLVHGSPGTGKSVATNLIARAIAEAENTSTYSLPPDPSHFD
GYKQQGVVIMDDLNQGADMKLFCQMVSTVEFIPPMASLAEAGILFTSNYV
LASTNSSDALARRFAFDMDIQVMNEYSRDGKLNMAMATEMCKNCHQPANF
KRCCPLVCGKAIQLMDKSSRVRYSIDQITTMIINERNRRSNIGNCMEALF
Q
3D structure
PDB5z3q Crystal structure of a soluble fragment of poliovirus 2CATPase
ChainE
Resolution2.545 Å
3D
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E C269 C272 C281 C286 C141 C144 C153 C158
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003724 RNA helicase activity

View graph for
Molecular Function
External links
PDB RCSB:5z3q, PDBe:5z3q, PDBj:5z3q
PDBsum5z3q
PubMed30231078
UniProtP03300|POLG_POL1M Genome polyprotein

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