Structure of PDB 5yi3 Chain E

Receptor sequence
>5yi3E (length=145) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence]
MSLANQIDQFLGTIMQFAENKHEILLGKSESDVKLTSTQEHILMLLAEQI
STNAKIAEKLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEKA
VPVAKEHATHHEKTLSTYQELGNKFTDEEQEVISKFLSALTEEFQ
3D structure
PDB5yi3 Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
ChainE
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E T37 T39 S64 A67 T36 T38 S63 A66 PDBbind-CN: Kd=0.55uM
BS02 dna E N54 A55 P65 A66 T69 N53 A54 P64 A65 T68 PDBbind-CN: Kd=0.55uM
BS03 dna E T53 V92 T52 V91 PDBbind-CN: Kd=0.55uM
BS04 ZN E E24 H42 H108 H112 E23 H41 H107 H111
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5yi3, PDBe:5yi3, PDBj:5yi3
PDBsum5yi3
PubMed29229866
UniProtQ9CDU5

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