Structure of PDB 5yi2 Chain E

Receptor sequence
>5yi2E (length=146) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence]
GMSLANQIDQFLGTIMQFAENKHEILLGKCESDVKLTSTQEHILMLLAEQ
ISTNAKIAEKLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEK
AVPVAKEHATHHEKTLSTYQELGNKFTDEEQEVISKFLSALTEEFQ
3D structure
PDB5yi2 Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
ChainE
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E T37 S64 A67 K70 T37 S64 A67 K70 PDBbind-CN: Kd=72nM
BS02 dna E T53 A55 K56 V92 T53 A55 K56 V92 PDBbind-CN: Kd=72nM
BS03 dna E N54 A55 P65 T69 K73 N54 A55 P65 T69 K73 PDBbind-CN: Kd=72nM
BS04 ZN E E24 H42 H108 H112 E24 H42 H108 H112
BS05 ZN E C30 E41 E107 C30 E41 E107
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5yi2, PDBe:5yi2, PDBj:5yi2
PDBsum5yi2
PubMed29229866
UniProtQ9CDU5

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