Structure of PDB 5xv0 Chain E

Receptor sequence
>5xv0E (length=223) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]
DRPFIFINSAMSADGKLSTKERKQVKISGKLNFERMDELRAHADAIMVGI
GTVLADDPSLTVKSPERKAARKAAGKSENPVRVVVDSSARTPLNADIFKK
GEGLRIIAVSNSAPEEKIRMLEEKALVIKTGAFRVDLTELAAKLKEMGIN
SLMVEGGATLNWGMLSAGLVDEVYTFVGNLIIGGKTAPTFTDGEGFTENE
LLGLELSSAEKIEDGILLKWKVK
3D structure
PDB5xv0 Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
ChainE
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.302: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP E S10 A11 L18 S19 R23 G50 I51 G52 T53 D57 V86 S88 V136 L138 G158 A159 T160 L161 S9 A10 L17 S18 R22 G49 I50 G51 T52 D56 V85 S87 V135 L137 G157 A158 T159 L160
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0009231 riboflavin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5xv0, PDBe:5xv0, PDBj:5xv0
PDBsum5xv0
PubMed29864427
UniProtQ8PYN5

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