Structure of PDB 5xr3 Chain E

Receptor sequence
>5xr3E (length=285) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
LSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLM
IAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVK
LELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIP
GGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSP
LEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTG
RTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
3D structure
PDB5xr3 Structural and functional studies of SAV0551 fromStaphylococcus aureusas a chaperone and glyoxalase III.
ChainE
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.2.-
3.5.1.-
3.5.1.124: protein deglycase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLV E D177 D181 D170 D174
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016790 thiolester hydrolase activity
GO:0019172 glyoxalase III activity
GO:0036524 protein deglycase activity
Biological Process
GO:0006281 DNA repair
GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
GO:0019249 lactate biosynthetic process
GO:0030091 protein repair
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5xr3, PDBe:5xr3, PDBj:5xr3
PDBsum5xr3
PubMed29046369
UniProtP64312|HCHA_STAAM Protein/nucleic acid deglycase HchA (Gene Name=hchA)

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