Structure of PDB 5wre Chain E

Receptor sequence
>5wreE (length=142) Species: 10407 (Hepatitis B virus) [Search protein sequence]
MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSP
HHTALRQAILCWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQL
LWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILST
3D structure
PDB5wre Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
ChainE
Resolution1.946 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7TL E V124 W125 R127 T128 A132 P134 V124 W125 R127 T128 A132 P134 MOAD: ic50=0.39uM
BS02 7TL E F23 P25 L30 T33 W102 I105 S106 T109 F110 Y118 I139 L140 S141 F23 P25 L30 T33 W102 I105 S106 T109 F110 Y118 I139 L140 S141 MOAD: ic50=0.39uM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:5wre, PDBe:5wre, PDBj:5wre
PDBsum5wre
PubMed28205569
UniProtL7R9I1

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