Structure of PDB 5ujt Chain E

Receptor sequence
>5ujtE (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTP
LGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTIS
PSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGD
WTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRA
3D structure
PDB5ujt C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
ChainE
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E F11 G13 L26 Y30 Y37 A57 Y60 W61 E74 V78 H81 N82 L85 F9 G11 L24 Y28 Y35 A55 Y58 W59 E72 V76 H79 N80 L83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5ujt, PDBe:5ujt, PDBj:5ujt
PDBsum5ujt
PubMed29255035
UniProtO19707

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