Structure of PDB 5the Chain E

Receptor sequence
>5theE (length=514) Species: 436907 (Vanderwaltozyma polyspora DSM 70294) [Search protein sequence]
SIYKVENRHDYGTKGTKVDILTGSGRVPSRILDAPVVQFKESTFEYKDKS
YGTKHEESKGNWNMKGHQFISTPAKQVNLRAIFINNANTAPPASMESELD
ISMDKFASDVKQLGVDFNVSGKPILINQFGPPIKKFQPTFETSPGEISLL
NLLENIPSNTYILYVLRRGNDSAVYDRLKYITDLKFGALNSCVVWDNFKK
NSIQYNSNVVMKMNLKLLGSNHSLSIENNKLLIDKESNLPILVLGSDVTH
YPEKDQNSIASLVGSYDDKFTQFPGDYMLQDGPGEEIITNVGSLMLNRLK
IYQKHNNGKLPTKIMYFRDGVSVDQFSQVVKIEVKSIKESVRKFGPQLNG
GNKYDPPVTCIATVKRNQVRFIPIQENAKNEKGEEVAVQSMGNVMPGTVV
DRGITSVAHFDFFIQSHQALKGTGVPCHYWCLYDENQSTSDYLQEICNNL
CYIFGRSTTSVKVPAPVYYADLLCTRATCFFKAGFELNMAQATVSKNVLL
PQVNDNIKSVMYYI
3D structure
PDB5the Structural and functional analyses reveal the contributions of the C- and N-lobes of Argonaute protein to selectivity of RNA target cleavage.
ChainE
Resolution2.097 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E S899 Y902 K906 S918 C919 V921 N924 Y932 N935 V936 K939 R1093 H1144 L1147 K1148 G1151 F1181 R1183 S1184 T1186 V1188 K1189 Y1195 S172 Y175 K179 S191 C192 V194 N197 Y205 N208 V209 K212 R366 H417 L420 K421 G424 F454 R456 S457 T459 V461 K462 Y468
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:5the, PDBe:5the, PDBj:5the
PDBsum5the
PubMed29519815
UniProtA7TMA9

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