Structure of PDB 5t2p Chain E

Receptor sequence
>5t2pE (length=150) Species: 10407 (Hepatitis B virus) [Search protein sequence]
MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSP
HHTALRQAILCWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQL
LWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLVENLYFQ
3D structure
PDB5t2p Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
ChainE
Resolution1.693 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K89 E W125 T128 P134 W125 T128 P134 MOAD: ic50=1.9uM
BS02 K89 E P25 L30 T33 W102 I105 F110 Y118 I139 L140 P25 L30 T33 W102 I105 F110 Y118 I139 L140 MOAD: ic50=1.9uM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:5t2p, PDBe:5t2p, PDBj:5t2p
PDBsum5t2p
PubMed28205569
UniProtL7R9I1

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