Structure of PDB 5onb Chain E

Receptor sequence
>5onbE (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]
LEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAAL
LQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIP
LFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPL
CLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKM
VLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVL
KDDTTTKRWLAQLVKNLQE
3D structure
PDB5onb DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
ChainE
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E E47 H85 N88 Q98 R130 Y134 L137 T138 G141 K148 L177 F184 H231 E31 H69 N72 Q82 R114 Y118 L121 T122 G125 K132 L161 F168 H215
Gene Ontology
Biological Process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0030014 CCR4-NOT complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5onb, PDBe:5onb, PDBj:5onb
PDBsum5onb
PubMed29255063
UniProtQ92600|CNOT9_HUMAN CCR4-NOT transcription complex subunit 9 (Gene Name=CNOT9)

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