Structure of PDB 5ona Chain E

Receptor sequence
>5onaE (length=271) Species: 9606 (Homo sapiens) [Search protein sequence]
HMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIA
ALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAH
IPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEII
PLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILG
KMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQ
VLKDDTTTKRWLAQLVKNLQE
3D structure
PDB5ona DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
ChainE
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E N88 R130 E133 Y134 L137 T138 L177 V181 F184 H231 N74 R116 E119 Y120 L123 T124 L163 V167 F170 H217
Gene Ontology
Biological Process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0030014 CCR4-NOT complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5ona, PDBe:5ona, PDBj:5ona
PDBsum5ona
PubMed29255063
UniProtQ92600|CNOT9_HUMAN CCR4-NOT transcription complex subunit 9 (Gene Name=CNOT9)

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