Structure of PDB 5o96 Chain E

Receptor sequence
>5o96E (length=242) Species: 446 (Legionella pneumophila) [Search protein sequence]
VRTIRIYQPGEYQPGQLLELSPEAGQHVGVVLRMEQGEQLTLFNGDNKEF
TASIERVKKKQVFVRIASVLEVNRESPLKIHLAQAISKGERMEMVMQKSA
ELGVACITPLITERCQVKIDKEKMAKKMHQWLNIIIGACEQCGRNQIPEL
RQPVYLDQFVREAKEHLKLILHPAFSKTWRDYPVQPPDVALIIGPEGGFS
DEEIRLTSGHGFLPLSLGPRVLRTETAAITALSVLQAAGGDL
3D structure
PDB5o96 Crystal structure of the Legionella pneumophila Lpg2936 in complex with the cofactor S-adenosyl-L-methionine reveals novel insights into the mechanism of RsmE family methyltransferases.
ChainE
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM E L173 P175 P197 E198 S218 L219 G220 R222 V223 L224 R225 L171 P173 P195 E196 S216 L217 G218 R220 V221 L222 R223 MOAD: Ka=708000M^-1
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0070042 rRNA (uridine-N3-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5o96, PDBe:5o96, PDBj:5o96
PDBsum5o96
PubMed28940762
UniProtQ5ZRE6

[Back to BioLiP]