Structure of PDB 5o4y Chain E

Receptor sequence
>5o4yE (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAAYA
3D structure
PDB5o4y Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Y56 N63 Q66 V68 D73 V76 R113 M115 Y123 Y39 N46 Q49 V51 D56 V59 R96 M98 Y106
BS02 peptide E E60 V111 R125 T127 E43 V94 R108 T110
External links
PDB RCSB:5o4y, PDBe:5o4y, PDBj:5o4y
PDBsum5o4y
PubMed28881104
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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