Structure of PDB 5o32 Chain E

Receptor sequence
>5o32E (length=640) Species: 9606 (Homo sapiens) [Search protein sequence]
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSE
KTVLTPATNHMGNVTFTIPANREFKKGRNKFVTVQATFGTQVVEKVVLVS
LQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIP
VKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEV
KEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFG
IQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSL
YVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMV
FVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITV
RTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVN
FLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTD
FIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQ
PVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKAD
IGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQ
3D structure
PDB5o32 Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
ChainE
Resolution4.20621 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA E D554 D557 D530 D533
Gene Ontology
Molecular Function
GO:0004866 endopeptidase inhibitor activity

View graph for
Molecular Function
External links
PDB RCSB:5o32, PDBe:5o32, PDBj:5o32
PDBsum5o32
PubMed28671664
UniProtP01024|CO3_HUMAN Complement C3 (Gene Name=C3)

[Back to BioLiP]