Structure of PDB 5njk Chain E

Receptor sequence
>5njkE (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKAVKA
VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTT
RRWICHCFMAVKDTGERLSHAVGCAFAACLERK
3D structure
PDB5njk A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
ChainE
Resolution3.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E R53 E112 K113 V114 S115 F116 C117 R132 W139 S155 H156 F162 R26 E76 K77 V78 S79 F80 C81 R96 W103 S119 H120 F126
BS02 peptide E K63 K66 F123 K36 K39 F87
External links
PDB RCSB:5njk, PDBe:5njk, PDBj:5njk
PDBsum5njk
PubMed29269425
UniProtP49757|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)

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