Structure of PDB 5ksu Chain E

Receptor sequence
>5ksuE (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTL
LGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS
PSNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWR
3D structure
PDB5ksu Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
ChainE
Resolution2.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E F11 F47 Y60 W61 R77 V78 H81 N82 L85 F9 F45 Y58 W59 R75 V76 H79 N80 L83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5ksu, PDBe:5ksu, PDBj:5ksu
PDBsum5ksu
PubMed28364043
UniProtQ5Y7D3

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