Structure of PDB 5kra Chain E

Receptor sequence
>5kraE (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVPLSDLLLEMLDAHR
3D structure
PDB5kra Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainE
Resolution2.401 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E I358 K362 L372 V376 E380 D538 L539 E542 I49 K53 L63 V67 E71 D218 L219 E222
BS02 6WS E L346 A350 E353 F404 M421 I424 F425 L525 L37 A41 E44 F95 M112 I115 F116 L206
External links
PDB RCSB:5kra, PDBe:5kra, PDBj:5kra
PDBsum5kra
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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