Structure of PDB 5k83 Chain E

Receptor sequence
>5k83E (length=191) Species: 9544 (Macaca mulatta) [Search protein sequence]
MKPQIRNMVEPMDPRTFVSNFNNRPILSGLDTVWLCCEVKTKDPSGPPLD
AKIFQGKVYPKAKYHPEMRFLRWFHKWRQLHHDQEYKVTWYVSWSPCTRC
ANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILAEAGATMKIMNY
NEFQDCWNKFVDGRGKPFKPWNNLPKHYTLLQATLGELLRH
3D structure
PDB5k83 Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
ChainE
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.-
3.5.4.38: single-stranded DNA cytosine deaminase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E Y59 P60 K61 H65 W94 S95 Y124 Y125 Y59 P60 K61 H65 W94 S95 Y124 Y125 PDBbind-CN: Kd=1.57uM
BS02 ZN E H65 C97 C100 H65 C97 C100
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5k83, PDBe:5k83, PDBj:5k83
PDBsum5k83
PubMed27480941
UniProtM1GSK9

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