Structure of PDB 5j9q Chain E

Receptor sequence
>5j9qE (length=293) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SMTQNPHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTL
QYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLC
LLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNV
ACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPQKPLSDLGLLSYRAY
WSDTLITLLVEHQKEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHI
IFLNEDILDRYNRLKAKKRRTIDPNRLIWKPPVFTASQLRFAW
3D structure
PDB5j9q The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
ChainE
Resolution3.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C304 Q338
Catalytic site (residue number reindexed from 1) C152 Q186
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E H261 T263 F271 C304 Q338 P340 H109 T111 F119 C152 Q186 P188
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5j9q, PDBe:5j9q, PDBj:5j9q
PDBsum5j9q
PubMed27594449
UniProtQ08649|ESA1_YEAST Histone acetyltransferase ESA1 (Gene Name=ESA1)

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