Structure of PDB 5j0n Chain E

Receptor sequence
>5j0nE (length=274) Species: 10710 (Lambdavirus lambda) [Search protein sequence]
NSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITT
KEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNHVAATRAA
KSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKW
SDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMKETLDKCKEILGGETI
IASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQ
ISDKFAQHLLGHKSDTEWDKIEIK
3D structure
PDB5j0n Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
ChainE
Resolution11.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E K136 S139 V175 R176 R177 K235 S281 Y288 H333 K65 S68 V104 R105 R106 K164 S210 Y217 H262
BS02 dna E I92 K93 T96 N99 R177 S234 K235 M290 R293 T306 H308 I21 K22 T25 N28 R106 S163 K164 M219 R222 T235 H237
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008907 integrase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032359 provirus excision
GO:0044826 viral genome integration into host DNA
GO:0046718 symbiont entry into host cell
GO:0075713 establishment of integrated proviral latency

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Molecular Function
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Biological Process
External links
PDB RCSB:5j0n, PDBe:5j0n, PDBj:5j0n
PDBsum5j0n
PubMed27223329
UniProtP03700|VINT_LAMBD Integrase (Gene Name=int)

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