Structure of PDB 5iy9 Chain E

Receptor sequence
>5iy9E (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSE
GRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENIT
RALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVV
MTKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETA
GRYITYRLVQ
3D structure
PDB5iy9 Near-atomic resolution visualization of human transcription promoter opening.
ChainE
Resolution6.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E K81 I84 T111 K81 I84 T111
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0001055 RNA polymerase II activity
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006362 transcription elongation by RNA polymerase I
GO:0006366 transcription by RNA polymerase II
GO:0042797 tRNA transcription by RNA polymerase III
GO:0050821 protein stabilization
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005666 RNA polymerase III complex
GO:0005730 nucleolus
GO:0005736 RNA polymerase I complex
GO:0005829 cytosol
GO:1990062 RPAP3/R2TP/prefoldin-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5iy9, PDBe:5iy9, PDBj:5iy9
PDBsum5iy9
PubMed27193682
UniProtP19388|RPAB1_HUMAN DNA-directed RNA polymerases I, II, and III subunit RPABC1 (Gene Name=POLR2E)

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