Structure of PDB 5iuj Chain E

Receptor sequence
>5iujE (length=215) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
GRKERERLEEKLEDANERIAELVKLEERQRIARDLEDTLGQKLSLIGLKS
DLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELIN
IKQILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKT
CRVDIQQLWKEVVITVSDDGTFKGEENSFSKGHGLLGMRERLEFANGSLH
IDTENGTKLTMAIPN
3D structure
PDB5iuj Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
ChainE
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP E E289 N293 H297 S298 T323 F324 K325 G326 H335 G336 L337 T359 E137 N141 H145 S146 T171 F172 K173 G174 H183 G184 L185 T207
BS02 MG E E289 N293 E137 N141
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000160 phosphorelay signal transduction system
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5iuj, PDBe:5iuj, PDBj:5iuj
PDBsum5iuj
PubMed27938660
UniProtO34757|DESK_BACSU Sensor histidine kinase DesK (Gene Name=desK)

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