Structure of PDB 5fb3 Chain E

Receptor sequence
>5fb3E (length=334) Species: 410359 (Pyrobaculum calidifontis JCM 11548) [Search protein sequence]
KKVERFEVPRTIIFGPGALEKTPEVIPPSGRVLIITGKSSTRKYAERVAE
LLKQNCEIISYDQVELEKPGFDLVIGIGGGRPLDMAKVYSYIHKKPFVAI
PTSASHDGIASPYVSFSLTQRFSKYGKISSSPVAIIADTSIILSAPSRLL
KAGIGDLLGKIIAVRDWQLAHRLKGEEYSEYAAHLSLTSYKIAVGNAQKI
KNFIREEDVRVLVKALIGCGVAMGIAGSSRPCSGSEHLFAHAIEVRVDEV
VHGELVALGTIIMAYLHGINWRRIKRIADIIGLPTSLRQANIDVDLALEA
LTTAHTLRPDRYTILGDGLSREAAKRALEDVELI
3D structure
PDB5fb3 Unique coenzyme binding mode of hyperthermophilic archaeal sn-glycerol-1-phosphate dehydrogenase from Pyrobaculum calidifontis
ChainE
Resolution2.45 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D157 H238 A241 H256
Catalytic site (residue number reindexed from 1) D156 H237 A240 H252
Enzyme Commision number 1.1.1.261: sn-glycerol-1-phosphate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP E G38 K39 S40 T42 G80 G81 R82 D85 T103 S106 H107 Y114 V115 S116 I142 S145 A146 L150 H256 G37 K38 S39 T41 G79 G80 R81 D84 T102 S105 H106 Y113 V114 S115 I141 S144 A145 L149 H252
BS02 ZN E D157 H238 H256 D156 H237 H252
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0046872 metal ion binding
GO:0050492 glycerol-1-phosphate dehydrogenase [NAD(P)+] activity
GO:0106357 glycerol-1-phosphate dehydrogenase (NAD+) activity
GO:0106358 glycerol-1-phosphate dehydrogenase (NADP+) activity
Biological Process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:5fb3, PDBe:5fb3, PDBj:5fb3
PDBsum5fb3
PubMed27616573
UniProtA3MTM6|G1PDH_PYRCJ Glycerol-1-phosphate dehydrogenase [NAD(P)+] (Gene Name=egsA)

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