Structure of PDB 5exf Chain E

Receptor sequence
>5exfE (length=483) Species: 1104324 (Pyrobaculum ferrireducens) [Search protein sequence]
KVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFE
ALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEV
VFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYP
LSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLV
IGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGS
DPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERY
VHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGG
RSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTD
YGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGV
GREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL
3D structure
PDB5exf NADP-Dependent Aldehyde Dehydrogenase from ArchaeonPyrobaculum sp.1860: Structural and Functional Features.
ChainE
Resolution2.19 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N155 K178 E253 C287 E382 E460
Catalytic site (residue number reindexed from 1) N148 K171 E246 C280 E375 E453
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP E I151 T152 P153 W154 N155 I160 K178 P179 A180 S181 P210 G211 G215 F229 T230 G231 E232 T235 I239 E253 L254 C287 E382 F384 I144 T145 P146 W147 N148 I153 K171 P172 A173 S174 P203 G204 G208 F222 T223 G224 E225 T228 I232 E246 L247 C280 E375 F377
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

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Molecular Function
External links
PDB RCSB:5exf, PDBe:5exf, PDBj:5exf
PDBsum5exf
PubMed27956891
UniProtG7VCG0

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