Structure of PDB 5esv Chain E

Receptor sequence
>5esvE (length=176) Species: 11676,71421 [Search protein sequence]
SLIRIGHGFDVHAFGCVTLNCSDAKVNINREEIKNCSFNATTELRDKKKK
EYALFYRLDIVPLNNSEYRLINCNGGDVALHALTDAILGAAALGDIGNAD
SRGLLREAFRQVQEKGYKIGNVDITIIAQAPPHIDAMRAKIAEDLQCDIE
QVNVKATTTEIACEAVALLIRQGLEV
3D structure
PDB5esv Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
ChainE
Resolution3.105 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.12: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E D120 H122 H207 D10 H12 H81
Gene Ontology
Molecular Function
GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Biological Process
GO:0016114 terpenoid biosynthetic process
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5esv, PDBe:5esv, PDBj:5esv
PDBsum5esv
PubMed26689967
UniProtP44815|ISPF_HAEIN 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Gene Name=ispF);
W6ICC0

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