Structure of PDB 5e4h Chain E

Receptor sequence
>5e4hE (length=250) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
SETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLGVG
TDENYPLGTTTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKASRE
LYFEDVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPSSNGQPI
LCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVDIQ
GVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDVK
3D structure
PDB5e4h Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation.
ChainE
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.7: [myosin heavy-chain] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H742 H794 C796 C800 H184 H236 C238 C242
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5e4h, PDBe:5e4h, PDBj:5e4h
PDBsum5e4h
PubMed27211275
UniProtP42527|MHCKA_DICDI Myosin heavy chain kinase A (Gene Name=mhkA)

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