Structure of PDB 5dqr Chain E

Receptor sequence

>5dqrE (length=406) Species: 3702 (Arabidopsis thaliana)

TYPAKDHCSQCGLCDTYYIAHVKEACAFLGDGMSRIESLEPVVHGRGRKA
DSLQDTYFGVHQEQLYARKLKPVEGAQWTGIVTTIAIEMLKSNMVEAVVC
VQSDPEDRLSPRPVLARTPEEVLAARGVKPTLSPNLNTLELIEASGVKRL
LFCGVGCQVQALRSVEQHLNLEKLYVLGTNCVDNGTRDGLDKFLKAASKE
PETVLHYEFMQDYKVQLKHLDGHIEEVPYFSLPANDLVDVIAPSCYSCFD
YTNALADLVIGYMGVPKYSGLNMTDHPQYITVRNERGKEMLSLVENLLEI
TPTISSGDRRPFVTETVKADDAAKFGQAQPAPLFVGNIIAFILNLVGPKG
LEFARYSLDYHTIRNYLYVNRKWGKQRANTHMPSYAKKIVEMYNKNGQID
KMLSKK

3D structure

• PDB: 5dqr Crystal Structure and Catalytic Mechanism of 7-Hydroxymethyl Chlorophyll a Reductase
• Chain: E
• Resolution: 2.7 Å

Enzymatic activity

• Enzyme Commision number: 1.17.7.2: 7-hydroxymethyl chlorophyll a reductase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SF4	E	Y56 A58 C62 S63 Q64 C65 L67 C68 V76 C80	Y2 A4 C8 S9 Q10 C11 L13 C14 V22 C26
BS02	SF4	E	S63 V209 C211 C235 V236 N238 S298 C299 C302	S9 V155 C157 C181 V182 N184 S244 C245 C248
BS03	FAD	E	Q131 W132 G134 I135 V136 T137 V155 A179 G181 V182 K183 S187 T233 N234 C235 I314 G315 Y316 M317 Q332	Q77 W78 G80 I81 V82 T83 V101 A125 G127 V128 K129 S133 T179 N180 C181 I260 G261 Y262 M263 Q278

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051536 iron-sulfur cluster binding
• GO:0090415 7-hydroxymethyl chlorophyll a reductase activity

Biological Process

• GO:0015994 chlorophyll metabolic process
• GO:0033354 chlorophyll cycle

Cellular Component

• GO:0005576 extracellular region
• GO:0009507 chloroplast

External links

• PDB: RCSB:5dqr, PDBe:5dqr, PDBj:5dqr
• PDBsum: 5dqr
• PubMed: 27072131
• UniProt: Q8GS60|HCAR_ARATH 7-hydroxymethyl chlorophyll a reductase, chloroplastic (Gene Name=HCAR)