Structure of PDB 5dnm Chain E

Receptor sequence
>5dnmE (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB5dnm Allosteric cross-talk in chromatin can mediate drug-drug synergy
ChainE
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E H39 R40 Y41 P43 G44 V46 A47 R49 R63 K64 L65 R69 R83 H2 R3 Y4 P6 G7 V9 A10 R12 R26 K27 L28 R32 R46
BS02 dna E R40 R42 T45 R72 R83 Q85 R116 V117 T118 R3 R5 T8 R35 R46 Q48 R79 V80 T81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5dnm, PDBe:5dnm, PDBj:5dnm
PDBsum5dnm
PubMed28358030
UniProtP84233|H32_XENLA Histone H3.2

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