Structure of PDB 5d6s Chain E

Receptor sequence

>5d6sE (length=370) Species: 1308 (Streptococcus thermophilus) [Search protein sequence]

MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKN
IEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLD
YHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGK
NGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLI
GDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGID
NPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIAL
ANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGL
SPKDEHSQAEWELVCAKWQI

3D structure

PDB

5d6s Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification.

Chain

Resolution

2.65 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SF4	E	C184 C187 C190 C243 P244 Y245	C184 C187 C190 C243 P244 Y245
BS02	SF4	E	C194 P195 C198 L199 C210 L211 C236 C239	C194 P195 C198 L199 C210 L211 C236 C239
BS03	B12	E	Y29 L30 L34 T44 R54 T93 N95 D130 D136 T137 K141 I148 G152 V154 M163 L165 T204 M205 S212 C236	Y29 L30 L34 T44 R54 T93 N95 D130 D136 T137 K141 I148 G152 V154 M163 L165 T204 M205 S212 C236

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding
GO:0052693	epoxyqueuosine reductase activity

	Biological Process
GO:0008033	tRNA processing
GO:0008616	queuosine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5d6s, PDBe:5d6s, PDBj:5d6s
PDBsum	5d6s
PubMed	26378237
UniProt	A0A0R4I997

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