Structure of PDB 5c7k Chain E

Receptor sequence
>5c7kE (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
QIHLVQSGTEVKKPGSSVTVSCKAYGVNTFGLYAVNWVRQAPGQSLEYIG
QIWRWKSSASHHFRGRVLISAVDLTGSSPPISSLEIKNLTSDDTAVYFCT
TTSTYDKWSGLHHDGVMAFSSWGQGTLISVSAASTKGPSVFPLAPSSGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
TQTYICNVNHKPSNTKVDKKVEPK
3D structure
PDB5c7k Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
ChainE
Resolution4.6019 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA E S70 A71 S70 A71
BS02 MAN E S70 S78 S79 S70 S82 S83
BS03 MAN E T19 E81 T19 E85
BS04 MAN E S57 L68 S57 L68
BS05 MAN E S58 A59 R64 G65 V67 L68 S58 A59 R64 G65 V67 L68
External links
PDB RCSB:5c7k, PDBe:5c7k, PDBj:5c7k
PDBsum5c7k
PubMed26457433
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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