Structure of PDB 5bs0 Chain E

Receptor sequence
>5bs0E (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
AGVTQTPRYLIKTRGQQVTLSCSPISGHRSVSWYQQTPGQGLQFLFEYFS
ETQRNKGNFPGRFSGRQFSNSRSEMNVSTLELGDSALYLCASSFNMATGQ
YFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPD
HVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQD
PRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
3D structure
PDB5bs0 Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
ChainE
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E F51 N97 F49 N95
External links
PDB RCSB:5bs0, PDBe:5bs0, PDBj:5bs0
PDBsum5bs0
PubMed26758806
UniProtA0A578;
A0A5B9|TRBC2_HUMAN T cell receptor beta constant 2 (Gene Name=TRBC2)

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