Structure of PDB 5brm Chain E

Receptor sequence
>5brmE (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTI
LKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRREL
APLQELIEKL
3D structure
PDB5brm Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
ChainE
Resolution2.651 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E R92 Y93 E94 Y95 H96 D99 K153 R154 R157 Y163 F167 E176 E200 E206 L207 R41 Y42 E43 Y44 H45 D48 K102 R103 R106 Y112 F116 E125 E149 E155 L156
BS02 peptide E V62 N66 V11 N15
BS03 ZN E C79 C84 H161 H166 C28 C33 H110 H115
External links
PDB RCSB:5brm, PDBe:5brm, PDBj:5brm
PDBsum5brm
PubMed26108669
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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