Structure of PDB 5bjt Chain E

Receptor sequence
>5bjtE (length=263) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWE
NQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTS
VPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF
LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFY
PPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIV
QHAGLAQPLRVEL
3D structure
PDB5bjt Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
ChainE
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E Y60 N149 L152 T153 F157 H161 Y56 N145 L148 T149 F153 H157
BS02 peptide E F193 L240 T241 F189 L236 T237
BS03 peptide E T103 S104 V105 P106 L156 F157 T99 S100 V101 P102 L152 F153
BS04 peptide E Q261 R264 V265 Q257 R260 V261
External links
PDB RCSB:5bjt, PDBe:5bjt, PDBj:5bjt
PDBsum5bjt
PubMed28330995
UniProtP55899|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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