Structure of PDB 4zg4 Chain E

Receptor sequence
>4zg4E (length=711) Species: 9606 (Homo sapiens) [Search protein sequence]
MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLELDYSVNP
ESLPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGII
LVAMNPYKQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRN
QSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAHVEDKVLASNPITEAV
GNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVFQSENE
RNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMV
ETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSH
LKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKK
IYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINY
ANEKLQQQFNMHVFKLEQEEYMKEDIWTLIDFYDNQPVIDLIEAKMGILE
LLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNTSFVIQHFADKV
EYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENRTTVGSKFRSSL
YLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRIS
AQSYPWTYIEFYSRYGILKQELSFVCKVVLHRLIQDSNQYQFGKTKIFFR
AVAYLEKLRLD
3D structure
PDB4zg4 Force-producing ADP state of myosin bound to actin.
ChainE
Resolution2.36 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S163 T168 S215 S216
Catalytic site (residue number reindexed from 1) S159 T164 S211 S212
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E T168 S216 T164 S212
BS02 ADP E N109 P110 K112 G164 G166 K167 T168 V169 N212 N105 P106 K108 G160 G162 K163 T164 V165 N208
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4zg4, PDBe:4zg4, PDBj:4zg4
PDBsum4zg4
PubMed26976594
UniProtQ9NQX4|MYO5C_HUMAN Unconventional myosin-Vc (Gene Name=MYO5C)

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