Structure of PDB 4z8l Chain E

Receptor sequence
>4z8lE (length=79) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence]
EAPEGAGEVGLEQWLETSLERINREARLHFHPEFLFRLWNTCVEHWHDRH
QRSLDYAKYRYLLLMHKAMYTHMQQGCPC
3D structure
PDB4z8l Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
ChainE
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H38 H81 C86 H29 H72 C77
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0019058 viral life cycle
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0042025 host cell nucleus
GO:0043657 host cell
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4z8l, PDBe:4z8l, PDBj:4z8l
PDBsum4z8l
PubMed26045556
UniProtQ7ZB17

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