Structure of PDB 4yb7 Chain E

Receptor sequence
>4yb7E (length=295) Species: 195099 (Campylobacter jejuni RM1221) [Search protein sequence]
TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVR
DDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYC
RLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGS
VEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSK
EKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTIL
PLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK
3D structure
PDB4yb7 Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.
ChainE
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E D55 D56 D51 D52
BS02 ATP E Q12 G15 R16 L17 R54 D55 N75 C104 L170 Q8 G11 R12 L13 R50 D51 N71 C100 L166
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4yb7, PDBe:4yb7, PDBj:4yb7
PDBsum4yb7
PubMed27191057
UniProtQ5HSJ4|HIS1_CAMJR ATP phosphoribosyltransferase (Gene Name=hisG)

[Back to BioLiP]