Structure of PDB 4yb6 Chain E

Receptor sequence
>4yb6E (length=293) Species: 195099 (Campylobacter jejuni RM1221) [Search protein sequence]
NTRLRIAIQKSGRLSKESIELLSECGVKMHISLIAFSTNLPIDILRVRDD
DIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRL
SLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVE
VAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEK
QALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPL
AHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK
3D structure
PDB4yb6 Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.
ChainE
Resolution1.98 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HIS E H232 S288 L290 H226 S282 L284
BS02 AMP E L170 S172 S173 G174 T176 L164 S166 S167 G168 T170
BS03 HIS E G247 V248 E249 R250 T252 V268 G241 V242 E243 R244 T246 V262
BS04 MG E S226 K227 S220 K221
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4yb6, PDBe:4yb6, PDBj:4yb6
PDBsum4yb6
PubMed27191057
UniProtQ5HSJ4|HIS1_CAMJR ATP phosphoribosyltransferase (Gene Name=hisG)

[Back to BioLiP]