Structure of PDB 4yb5 Chain E

Receptor sequence
>4yb5E (length=290) Species: 195099 (Campylobacter jejuni RM1221) [Search protein sequence]
TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVR
DDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYC
RLSLALPQELKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAP
RANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQAL
VDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHD
EKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK
3D structure
PDB4yb5 Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.
ChainE
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HIS E H232 S288 L290 H223 S279 L281 PDBbind-CN: -logKd/Ki=4.71,Kd=19.3uM
BS02 HIS E G247 V248 R250 T252 M267 V268 G238 V239 R241 T243 M258 V259 PDBbind-CN: -logKd/Ki=4.71,Kd=19.3uM
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4yb5, PDBe:4yb5, PDBj:4yb5
PDBsum4yb5
PubMed27191057
UniProtQ5HSJ4|HIS1_CAMJR ATP phosphoribosyltransferase (Gene Name=hisG)

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