Structure of PDB 4xl1 Chain E

Receptor sequence
>4xl1E (length=229) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GSSSIFQLRLQEFANERGMLANGRPCEPGCRTFFRICLKHYQATFSEGPC
TFGNVSTPVLGTNSFVIRDKNSGSGRNPLQLPLNFTWPGTFSLNIQAWHT
PGDDLRPETSPGNSLISQIIIQGSLAVGKNWKSDEQNNTLTRLRYSYRVV
CSDNYYGDSCSRLCKKRDDHFGHYECQPDGSPSCLPGWTGKYCDQPICLS
GCHEQNGYCSKPDECNCRPGWQGPLCNEA
3D structure
PDB4xl1 Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC E D218 Q219 D194 Q195
BS02 FUC E H64 Y65 H40 Y41
Gene Ontology
Biological Process
GO:0007154 cell communication
GO:0007219 Notch signaling pathway
GO:0007275 multicellular organism development
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:4xl1, PDBe:4xl1, PDBj:4xl1
PDBsum4xl1
PubMed25700513
UniProtD3ZHH1|DLL4_RAT Delta-like protein 4 (Gene Name=Dll4)

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