Structure of PDB 4xh2 Chain E

Receptor sequence

>4xh2E (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]

ISEVQLVESGGGLVQPGGSLRLSCAASGFNVSSYSIHWVRQAPGKGLEWV
AYISSSSGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCAR
TWYYGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTY
ICNVNHKPSNTKVDKKVEPK

3D structure

PDB

4xh2 Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.

Chain

Resolution

2.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	S31 Y32 S33 H35 Y50 Y56 Y58 T95 Y97 Y98	S33 Y34 S35 H37 Y52 Y59 Y61 T101 Y103 Y104

External links

PDB	RCSB:4xh2, PDBe:4xh2, PDBj:4xh2
PDBsum	4xh2
PubMed	26087144

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