Structure of PDB 4uov Chain E

Receptor sequence
>4uovE (length=225) Species: 228745 (Thermovibrio ammonificans) [Search protein sequence]
GAHWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVKACLAPVS
VYYVSDAKYVVNNGHTIKVVMGGRGYVVVDGKRFYLKQFHFHAPSEHTVN
GKHYPFEAHFVHLDKNGNITVLGVFFKVGKENPELEKVWRVMPEEPGQKR
HLTARIDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQL
EKFRKVMGFDNNRPVQPLNARKVMK
3D structure
PDB4uov The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability
ChainE
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H87 H112 H114 E118 H131 T198
Catalytic site (residue number reindexed from 1) H65 H90 H92 E96 H109 T176
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H112 H114 H131 H90 H92 H109
BS02 AZM E H112 H131 V133 L197 T198 T199 H90 H109 V111 L175 T176 T177
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:4uov, PDBe:4uov, PDBj:4uov
PDBsum4uov
PubMed25286845
UniProtE8T502

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