Structure of PDB 4unz Chain E

Receptor sequence
>4unzE (length=318) Species: 159470 (Influenza A virus (A/eq/Newmarket/93/(H3N8))) [Search protein sequence]
NNTATLCLGHHAVANGTLVKTITDDQIEVTNATELVQSISIGKICNNSYR
VLDGRNCTLIDAMLGDPHCDDFQYENWDLFIERSSAFSNCYPYDIPDYAS
LRSIVASSGTLEFTAEGFTWTGVTQNGGSGACKRGSADSFFSRLNWLTKS
GNSYPILNVTMPNNKNFDKLYIWGIHHPSSNKEQTKLYIQESGRVTVSTE
RSQQTVIPNIGSRPWVRGQSGRISIYWTIVKPGDILMINSNGNLVAPRGY
FKLRTGKSSVMRSDALIDTCVSECITPNGSIPNDKPFQNVNKITYGKCPK
YIRQNTLKLATGMRNVPE
3D structure
PDB4unz Recent Evolution of Equine Influenza and the Origin of Canine Influenza.
ChainE
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL E E190 Q226 E183 Q219
BS02 SIA E Y98 S136 G137 H183 E190 L194 Q226 Y91 S129 G130 H176 E183 L187 Q219
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4unz, PDBe:4unz, PDBj:4unz
PDBsum4unz
PubMed25024224
UniProtQ82847

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