Structure of PDB 4ru2 Chain E

Receptor sequence

>4ru2E (length=112) Species: 10090 (Mus musculus)

VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDK
YSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPD
SMTATQLLVPSR

3D structure

• PDB: 4ru2 Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Mus musculus at 2.20 A resolution
• Chain: E
• Resolution: 2.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	E445 D449 E453 L491 R494 W495 F496 A497 G498	E28 D32 E36 L74 R77 W78 F79 A80 G81

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding

Biological Process

• GO:0006397 mRNA processing

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:4ru2, PDBe:4ru2, PDBj:4ru2
• PDBsum: 4ru2
• UniProt: Q8VH51|RBM39_MOUSE RNA-binding protein 39 (Gene Name=Rbm39)