Structure of PDB 4qnk Chain E

Receptor sequence
>4qnkE (length=185) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLF
DVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLD
EALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTL
HIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
3D structure
PDB4qnk Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
ChainE
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN E H47 H169 E173 H39 H161 E165
BS02 MN E H73 E77 H145 H65 E69 H137
BS03 PO4 E Q51 H55 K177 Q43 H47 K169
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
Biological Process
GO:0000105 L-histidine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4qnk, PDBe:4qnk, PDBj:4qnk
PDBsum4qnk
PubMed26095028
UniProtO23346|HIS5B_ARATH Imidazoleglycerol-phosphate dehydratase 2, chloroplastic (Gene Name=HISN5B)

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