Structure of PDB 4qd2 Chain E

Receptor sequence
>4qd2E (length=212) Species: 10090 (Mus musculus) [Search protein sequence]
WVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVF
IIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQ
NDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIV
SQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGL
STTAKAVITVKD
3D structure
PDB4qd2 Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex.
ChainE
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA E E11 D67 E69 D103 E10 D66 E68 D102
BS02 CA E E11 E69 D100 Q101 D103 D136 E10 E68 D99 Q100 D102 D135
BS03 CA E N102 N104 D134 D136 N143 D195 N101 N103 D133 D135 N142 D194
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4qd2, PDBe:4qd2, PDBj:4qd2
PDBsum4qd2
PubMed24948737
UniProtP09803|CADH1_MOUSE Cadherin-1 (Gene Name=Cdh1)

[Back to BioLiP]