Structure of PDB 4pnf Chain E

Receptor sequence
>4pnfE (length=220) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQ
HTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHF
ESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYI
AGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEAN
GKGVRQLVAIFKKTNFTFEA
3D structure
PDB4pnf Comparison of epsilon- and delta-class glutathione S-transferases: the crystal structures of the glutathione S-transferases DmGSTE6 and DmGSTE7 from Drosophila melanogaster.
ChainE
Resolution2.11 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S12
Catalytic site (residue number reindexed from 1) S10
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH E P14 Q41 H53 T54 V55 S68 H69 F108 R113 P12 Q39 H51 T52 V53 S66 H67 F106 R111
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004364 glutathione transferase activity
Biological Process
GO:0006749 glutathione metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pnf, PDBe:4pnf, PDBj:4pnf
PDBsum4pnf
PubMed26457432
UniProtQ7JZM3

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