Structure of PDB 4pkh Chain E

Receptor sequence
>4pkhE (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQ
LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGF
ESATFLGYFKSGLKYKKGGVASGFG
3D structure
PDB4pkh Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
ChainE
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA E D136 G141 A143 D84 G89 A91
BS02 CA E G92 D93 E124 V172 G40 D41 E72 V120
Gene Ontology
Molecular Function
GO:0005523 tropomyosin binding
GO:0051015 actin filament binding
Biological Process
GO:0051694 pointed-end actin filament capping

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Molecular Function
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Biological Process
External links
PDB RCSB:4pkh, PDBe:4pkh, PDBj:4pkh
PDBsum4pkh
PubMed25061212
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN);
P28289

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