Structure of PDB 4ozt Chain E

Receptor sequence
>4oztE (length=238) Species: 121224 (Pediculus humanus corporis) [Search protein sequence]
VKPISPEQEELIHRLVYFQNEYEQPSDEDLKRISNTPSEGEDQSDLNFRH
ITEITILTVQLIVEFAKRLPGFDKLLREDQIALLKACSSEVMMLRMARRY
DVGSDSILFANNQPYTRDSYSLAGMGETVDDLLRFCRQMYGMKVDNAEYA
LLTAIVIFSERPSLIEGWKVEKIQEIYLEALKVYVDNRRKPASGTIFAKL
LSVLTELRTLGNLNSEMCFSLKLKNKKLPPFLAEIWDV
3D structure
PDB4ozt Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits.
ChainE
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P1A E E303 I334 T335 T338 R375 M376 F389 Y400 E23 I54 T55 T58 R95 M96 F109 Y120
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0035100 ecdysone binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0035076 ecdysone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4ozt, PDBe:4ozt, PDBj:4ozt
PDBsum4ozt
PubMed25004972
UniProtE0VVT4

[Back to BioLiP]