Structure of PDB 4ooa Chain E

Receptor sequence
>4ooaE (length=65) Species: 9606 (Homo sapiens) [Search protein sequence]
SLINLKIQKENPKVVNEINIEDLSLTKAAYCRCWRSKTFPACDGSCNKHN
ELTGDNVGPLILKKK
3D structure
PDB4ooa A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
ChainE
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES E C99 R100 C101 C110 D111 G112 S113 C114 P127 C31 R32 C33 C42 D43 G44 S45 C46 P59
Gene Ontology
Molecular Function
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0010506 regulation of autophagy
Cellular Component
GO:0043231 intracellular membrane-bounded organelle

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Cellular Component
External links
PDB RCSB:4ooa, PDBe:4ooa, PDBj:4ooa
PDBsum4ooa
PubMed24914968
UniProtQ8N5K1|CISD2_HUMAN CDGSH iron-sulfur domain-containing protein 2 (Gene Name=CISD2)

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